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A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the α-fetoprotein promoter
We examined the expression of the midkine (MK) and α-fetoprotein (AFP) genes in 15 paired human specimens obtained from hepatocellular carcinoma (HCC) and the corresponding noncancerous regions of the same patients. A total of 14 HCC but none of the noncancerous specimens were positive for the MK mR...
Autores principales: | Tomizawa, M, Yu, L, Wada, A, Tamaoki, T, Kadomatsu, K, Muramatsu, T, Matsubara, S, Watanabe, K, Ebara, M, Saisho, H, Sakiyama, S, Tagawa, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376946/ https://www.ncbi.nlm.nih.gov/pubmed/12966430 http://dx.doi.org/10.1038/sj.bjc.6601246 |
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