Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts

The Vaccine Research Center has developed a number of vaccine candidates for different diseases/infectious agents (HIV-1, Severe Acute Respiratory Syndrome virus, West Nile virus, and Ebola virus, plus a plasmid cytokine adjuvant—IL-2/Ig) based on a DNA plasmid vaccine platform. To support the clini...

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Detalles Bibliográficos
Autores principales: Sheets, Rebecca L., Stein, Judith, Manetz, T. Scott, Duffy, Chris, Nason, Martha, Andrews, Charla, Kong, Wing-Pui, Nabel, Gary J., Gomez, Phillip L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Safety Evaluation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377020/
https://www.ncbi.nlm.nih.gov/pubmed/16569729
http://dx.doi.org/10.1093/toxsci/kfj169

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