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Reversal of Taxol resistance in hepatoma by cyclosporin A: involvement of the PI-3 kinase-AKT 1 pathway

Hepatoma cells are known to be highly resistant to chemotherapy. Previously, we have found differential Taxol resistance in human and murine hepatoma cells. The aim of this study was to examine the effect of a multidrug resistance inhibitor, cyclosporin A in combination with Taxol on hepatoma in vit...

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Detalles Bibliográficos
Autores principales:	Lin, H-L, Lui, W-Y, Liu, T-Y, Chi, C-W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377082/ https://www.ncbi.nlm.nih.gov/pubmed/12644839 http://dx.doi.org/10.1038/sj.bjc.6600788

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