Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins

We address the problem of homology identification in complex multidomain families with varied domain architectures. The challenge is to distinguish sequence pairs that share common ancestry from pairs that share an inserted domain but are otherwise unrelated. This distinction is essential for accura...

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Detalles Bibliográficos
Autores principales: Song, Nan, Joseph, Jacob M., Davis, George B., Durand, Dannie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377100/
https://www.ncbi.nlm.nih.gov/pubmed/18475320
http://dx.doi.org/10.1371/journal.pcbi.1000063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377100/
https://www.ncbi.nlm.nih.gov/pubmed/18475320
http://dx.doi.org/10.1371/journal.pcbi.1000063

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