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Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins
We address the problem of homology identification in complex multidomain families with varied domain architectures. The challenge is to distinguish sequence pairs that share common ancestry from pairs that share an inserted domain but are otherwise unrelated. This distinction is essential for accura...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377100/ https://www.ncbi.nlm.nih.gov/pubmed/18475320 http://dx.doi.org/10.1371/journal.pcbi.1000063 |