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Cancer and the FRA3B/FHIT fragile locus: it's a HIT
The FHIT gene encompassing the most active common human chromosomal fragile region, FRA3B, was discovered in 1996 and proposed as a tumour suppressor gene for important human cancers. Seven years and more than 350 reports later, early questions concerning its tumour suppressor role have been answere...
Autores principales: | Huebner, K, Croce, C M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377116/ https://www.ncbi.nlm.nih.gov/pubmed/12771912 http://dx.doi.org/10.1038/sj.bjc.6600937 |
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