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Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10

Gelsolin expression is frequently downregulated in lung cancer and several types of different human cancers. To examine the effects of gelsolin restoration on tumorigenicity, we here stably expressed various levels of gelsolin via gene transfer in lung cancer cells (squamous cell carcinoma line, PC1...

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Detalles Bibliográficos
Autores principales: Sagawa, N, Fujita, H, Banno, Y, Nozawa, Y, Katoh, H, Kuzumaki, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377162/
https://www.ncbi.nlm.nih.gov/pubmed/12592377
http://dx.doi.org/10.1038/sj.bjc.6600739