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Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells
Previous studies detected both lethal and cumulative chromosomal aberrations in bone marrow and peripheral blood of patients with worn hip and knee replacements. This study shows that wear debris from a worn titanium metal on high-density polyethylene hip replacement also produces chromosomal instab...
Autores principales: | Coen, N, Kadhim, M A, Wright, E G, Case, C P, Mothersill, C E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377169/ https://www.ncbi.nlm.nih.gov/pubmed/12592368 http://dx.doi.org/10.1038/sj.bjc.6600758 |
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