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The parathyroid hormone-related protein receptor is expressed in breast cancer bone metastases and promotes autocrine proliferation in breast carcinoma cells
Overproduction of parathyroid hormone-related protein (PTHRP) occurs in a high proportion of primary breast cancers (PBC) and is strongly implicated in their metastatic spread to bone. Although the PTHRP-receptor (PTHRP-R) is often coexpressed with PTHRP in PBC, its role in regulating breast cancer...
Autores principales: | Hoey, R P, Sanderson, C, Iddon, J, Brady, G, Bundred, N J, Anderson, N G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377170/ https://www.ncbi.nlm.nih.gov/pubmed/12592371 http://dx.doi.org/10.1038/sj.bjc.6600757 |
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