Cargando…
Clinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomas
The presence of telomerase activity in a glioma may be a predictor of its malignant potential. Activation of telomerase is regulated at the transcriptional level of the human telomerase reverse transcriptase (hTERT). Here, we evaluated whether the amount of hTERT mRNA provides a molecular marker of...
Autores principales: | Tchirkov, A, Rolhion, C, Kémény, J-L, Irthum, B, Puget, S, Khalil, T, Chinot, O, Kwiatkowski, F, Périssel, B, Vago, P, Verrelle, P |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377176/ https://www.ncbi.nlm.nih.gov/pubmed/12592364 http://dx.doi.org/10.1038/sj.bjc.6600754 |
Ejemplares similares
-
Interleukin-6 gene amplification and shortened survival in glioblastoma patients
por: Tchirkov, A, et al.
Publicado: (2007) -
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
por: Lantuejoul, S, et al.
Publicado: (2004) -
Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes
por: Shin, K-H, et al.
Publicado: (2003) -
Comparison of the RNA-amplification based methods RT–PCR and NASBA for the detection of circulating tumour cells
por: Burchill, S A, et al.
Publicado: (2002) -
Real-time RT–PCR correlates with immunocytochemistry for the detection of disseminated epithelial cells in bone marrow aspirates of patients with breast cancer
por: Benoy, I H, et al.
Publicado: (2004)