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Methylation alterations are not a major cause of PTTG1 missregulation
BACKGROUND: On its physiological cellular context, PTTG1 controls sister chromatid segregation during mitosis. Within its crosstalk to the cellular arrest machinery, relies a checkpoint of integrity for which gained the over name of securin. PTTG1 was found to promote malignant transformation in 3T3...
Autores principales: | Hidalgo, Manuel, Galan, Jose Jorge, Sáez, Carmen, Ferrero, Eduardo, Castilla, Carolina, Ramirez-Lorca, Reposo, Pelaez, Pablo, Ruiz, Agustin, Japón, Miguel A, Royo, Jose Luis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377271/ https://www.ncbi.nlm.nih.gov/pubmed/18426563 http://dx.doi.org/10.1186/1471-2407-8-110 |
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