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Recent Insights in Islet Amyloid Polypeptide-Induced Membrane Disruption and Its Role in β-Cell Death in Type 2 Diabetes Mellitus

The presence of fibrillar protein deposits (amyloid) of human islet amyloid polypeptide (hIAPP) in the pancreatic islets of Langerhans is thought to be related to death of the insulin-producing islet β-cells in type 2 diabetes mellitus (DM2). The mechanism of hIAPP-induced β-cell death is not unders...

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Detalles Bibliográficos
Autores principales:	Khemtémourian, Lucie, Antoinette Killian, J., Höppener, Jo W. M., Engel, Maarten F. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2008
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377315/ https://www.ncbi.nlm.nih.gov/pubmed/18483616 http://dx.doi.org/10.1155/2008/421287

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