Specificity of the STAT4 Genetic Association for Severe Disease Manifestations of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...

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Detalles Bibliográficos
Autores principales: Taylor, Kimberly E., Remmers, Elaine F., Lee, Annette T., Ortmann, Ward A., Plenge, Robert M., Tian, Chao, Chung, Sharon A., Nititham, Joanne, Hom, Geoffrey, Kao, Amy H., Demirci, F. Yesim, Kamboh, M. Ilyas, Petri, Michelle, Manzi, Susan, Kastner, Daniel L., Seldin, Michael F., Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377340/
https://www.ncbi.nlm.nih.gov/pubmed/18516230
http://dx.doi.org/10.1371/journal.pgen.1000084

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