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Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant

BACKGROUND: In response to concerns expressed by workers at a public meeting, we analyzed the mortality experience of workers who were employed at the IBM plant in Endicott, New York and died between 1969–2001. An epidemiologic feasibility assessment indicated potential worker exposure to several kn...

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Detalles Bibliográficos
Autores principales: Clapp, Richard W, Hoffman, Kate
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383884/
https://www.ncbi.nlm.nih.gov/pubmed/18442394
http://dx.doi.org/10.1186/1476-069X-7-13
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author Clapp, Richard W
Hoffman, Kate
author_facet Clapp, Richard W
Hoffman, Kate
author_sort Clapp, Richard W
collection PubMed
description BACKGROUND: In response to concerns expressed by workers at a public meeting, we analyzed the mortality experience of workers who were employed at the IBM plant in Endicott, New York and died between 1969–2001. An epidemiologic feasibility assessment indicated potential worker exposure to several known and suspected carcinogens at this plant. METHODS: We used the mortality and work history files produced under a court order and used in a previous mortality analysis. Using publicly available data for the state of New York as a standard of comparison, we conducted proportional cancer mortality (PCMR) analysis. RESULTS: The results showed significantly increased mortality due to melanoma (PCMR = 367; 95% CI: 119, 856) and lymphoma (PCMR = 220; 95% CI: 101, 419) in males and modestly increased mortality due to kidney cancer (PCMR = 165; 95% CI: 45, 421) and brain cancer (PCMR = 190; 95% CI: 52, 485) in males and breast cancer (PCMR = 126; 95% CI: 34, 321) in females. CONCLUSION: These results are similar to results from a previous IBM mortality study and support the need for a full cohort mortality analysis such as the one being planned by the National Institute for Occupational Safety and Health.
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spelling pubmed-23838842008-05-14 Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant Clapp, Richard W Hoffman, Kate Environ Health Research BACKGROUND: In response to concerns expressed by workers at a public meeting, we analyzed the mortality experience of workers who were employed at the IBM plant in Endicott, New York and died between 1969–2001. An epidemiologic feasibility assessment indicated potential worker exposure to several known and suspected carcinogens at this plant. METHODS: We used the mortality and work history files produced under a court order and used in a previous mortality analysis. Using publicly available data for the state of New York as a standard of comparison, we conducted proportional cancer mortality (PCMR) analysis. RESULTS: The results showed significantly increased mortality due to melanoma (PCMR = 367; 95% CI: 119, 856) and lymphoma (PCMR = 220; 95% CI: 101, 419) in males and modestly increased mortality due to kidney cancer (PCMR = 165; 95% CI: 45, 421) and brain cancer (PCMR = 190; 95% CI: 52, 485) in males and breast cancer (PCMR = 126; 95% CI: 34, 321) in females. CONCLUSION: These results are similar to results from a previous IBM mortality study and support the need for a full cohort mortality analysis such as the one being planned by the National Institute for Occupational Safety and Health. BioMed Central 2008-04-28 /pmc/articles/PMC2383884/ /pubmed/18442394 http://dx.doi.org/10.1186/1476-069X-7-13 Text en Copyright © 2008 Clapp and Hoffman; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Clapp, Richard W
Hoffman, Kate
Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title_full Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title_fullStr Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title_full_unstemmed Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title_short Cancer mortality in IBM Endicott plant workers, 1969–2001: an update on a NY production plant
title_sort cancer mortality in ibm endicott plant workers, 1969–2001: an update on a ny production plant
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383884/
https://www.ncbi.nlm.nih.gov/pubmed/18442394
http://dx.doi.org/10.1186/1476-069X-7-13
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