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Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase

BACKGROUND: In order to maximize the useful therapeutic life of antimalarial drugs, it is crucial to understand the mechanisms by which parasites resistant to antimalarial drugs are selected and spread in natural populations. Recent work has demonstrated that pyrimethamine-resistance conferring muta...

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Detalles Bibliográficos
Autores principales:	Hawkins, Vivian N, Auliff, Alyson, Prajapati, Surendra Kumar, Rungsihirunrat, Kanchana, Hapuarachchi, Hapuarachchige C, Maestre, Amanda, O'Neil, Michael T, Cheng, Qin, Joshi, Hema, Na-Bangchang, Kesara, Sibley, Carol Hopkins
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383903/ https://www.ncbi.nlm.nih.gov/pubmed/18442404 http://dx.doi.org/10.1186/1475-2875-7-72

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