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Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
BACKGROUND: Circadian oscillation of clock-controlled gene expression is mainly regulated at the transcriptional level. Heterodimers of CLOCK and BMAL1 act as activators of target gene transcription; however, interactions of PER and CRY proteins with the heterodimer abolish its transcriptional activ...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383916/ https://www.ncbi.nlm.nih.gov/pubmed/18430226 http://dx.doi.org/10.1186/1471-2199-9-41 |