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Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex

BACKGROUND: The reduced folate carrier (RFC1) is an integral membrane protein and facilitative anion exchanger that mediates delivery of 5-methyltetrahydrofolate into mammalian cells. Adequate maternal-fetal transport of folate is necessary for normal embryogenesis. Targeted inactivation of the muri...

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Detalles Bibliográficos
Autores principales: Gelineau-van Waes, Janee, Maddox, Joyce R, Smith, Lynette M, van Waes, Michael, Wilberding, Justin, Eudy, James D, Bauer, Linda K, Finnell, Richard H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383917/
https://www.ncbi.nlm.nih.gov/pubmed/18400109
http://dx.doi.org/10.1186/1471-2164-9-156

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