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DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein

BACKGROUND: C-Myc is a short-lived oncoprotein that is destroyed by ubiquitin-mediated proteolysis. Dysregulated accumulation of c-Myc commonly occurs in human cancers. Some of those cases with the dysregulated c-Myc protein accumulation are attributed to gene amplification or increased mRNA express...

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Detalles Bibliográficos
Autores principales:	An, Jing, Yang, Dong-Yan, Xu, Qin-Zhi, Zhang, Shi-Meng, Huo, Yan-Ying, Shang, Zeng-Fu, Wang, Yu, Wu, De-Chang, Zhou, Ping-Kun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2383926/ https://www.ncbi.nlm.nih.gov/pubmed/18426604 http://dx.doi.org/10.1186/1476-4598-7-32

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