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Ligand Specificity of Group I Biotin Protein Ligase of Mycobacterium tuberculosis
BACKGROUND: Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis. Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed precurs...
Autores principales: | Purushothaman, Sudha, Gupta, Garima, Srivastava, Richa, Ramu, Vasanthakumar Ganga, Surolia, Avadhesha |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2384007/ https://www.ncbi.nlm.nih.gov/pubmed/18509457 http://dx.doi.org/10.1371/journal.pone.0002320 |
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