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Cellular pharmacokinetics of telavancin, a novel lipoglycopeptide antibiotic, and analysis of lysosomal changes in cultured eukaryotic cells (J774 mouse macrophages and rat embryonic fibroblasts)

BACKGROUND: Telavancin is a lipoglycopeptide with multiple mechanisms of action that include membrane-destabilizing effects towards bacterial cells. It shows bactericidal activity against forms of Staphylococcus aureus (phagolysosomal infection) with different resistance phenotypes [methicillin-resi...

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Detalles Bibliográficos
Autores principales:	Barcia-Macay, Maritza, Mouaden, Fatima, Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M., Van Bambeke, Françoise
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386079/ https://www.ncbi.nlm.nih.gov/pubmed/18375379 http://dx.doi.org/10.1093/jac/dkn120

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