The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila

Degradation of cytoplasmic components by autophagy requires the class III phosphatidylinositol 3 (PI(3))–kinase Vps34, but the mechanisms by which this kinase and its lipid product PI(3) phosphate (PI(3)P) promote autophagy are unclear. In mammalian cells, Vps34, with the proautophagic tumor suppres...

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Detalles Bibliográficos
Autores principales: Juhász, Gábor, Hill, Jahda H., Yan, Ying, Sass, Miklós, Baehrecke, Eric H., Backer, Jonathan M., Neufeld, Thomas P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386105/
https://www.ncbi.nlm.nih.gov/pubmed/18474623
http://dx.doi.org/10.1083/jcb.200712051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386105/
https://www.ncbi.nlm.nih.gov/pubmed/18474623
http://dx.doi.org/10.1083/jcb.200712051

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