Osseous metaplasia in an ulcerating tubular adenoma of the colon: a case report

INTRODUCTION: Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology. CASE PRESENTATION: A 63-year-old woman, who presented with a history of melaena,...

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Detalles Bibliográficos
Autores principales: White, Victoria, Shaw, Aidan G, Tierney, Gillian M, Lund, Jonathan N, Semeraro, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386133/
https://www.ncbi.nlm.nih.gov/pubmed/18445248
http://dx.doi.org/10.1186/1752-1947-2-130
Descripción
Sumario:INTRODUCTION: Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology. CASE PRESENTATION: A 63-year-old woman, who presented with a history of melaena, was found at colonoscopy to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma. CONCLUSION: Heterotopic ossification in colonic adenomas is a particularly rare phenomenon, with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear.

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