Enhancement of Both Long-Term Depression Induction and Optokinetic Response Adaptation in Mice Lacking Delphilin

In the cerebellum, Delphilin is expressed selectively in Purkinje cells (PCs) and is localized exclusively at parallel fiber (PF) synapses, where it interacts with glutamate receptor (GluR) δ2 that is essential for long-term depression (LTD), motor learning and cerebellar wiring. Delphilin ablation...

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Detalles Bibliográficos
Autores principales: Takeuchi, Tomonori, Ohtsuki, Gen, Yoshida, Takashi, Fukaya, Masahiro, Wainai, Tasuku, Yamashita, Manami, Yamazaki, Yoshito, Mori, Hisashi, Sakimura, Kenji, Kawamoto, Susumu, Watanabe, Masahiko, Hirano, Tomoo, Mishina, Masayoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386150/
https://www.ncbi.nlm.nih.gov/pubmed/18509461
http://dx.doi.org/10.1371/journal.pone.0002297

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