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Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese
BACKGROUND: Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the MMP1 gene was found significantly affecting promoter activity and corresponding tra...
Autores principales: | Song, You-Qiang, Ho, Daniel WH, Karppinen, Jaro, Kao, Patrick YP, Fan, Bao-Jian, Luk, Keith DK, Yip, Shea-Ping, Leong, John CY, Cheah, Kathryn SE, Sham, Pak, Chan, Danny, Cheung, Kenneth MC |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386444/ https://www.ncbi.nlm.nih.gov/pubmed/18439317 http://dx.doi.org/10.1186/1471-2350-9-38 |
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