M867, a Novel Selective Inhibitor of Caspase-3 Enhances Cell Death and Extends Tumor Growth Delay in Irradiated Lung Cancer Models

BACKGROUND: Lung cancer remains the leading cause of cancer death worldwide. Radioresistance of lung cancer cells results in unacceptable rate of loco-regional failure. Although radiation is known to induce apoptosis, our recent study showed that knockdown of pro-apoptotic proteins Bak and Bax resul...

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Detalles Bibliográficos
Autores principales: Kim, Kwang Woon, Moretti, Luigi, Lu, Bo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386548/
https://www.ncbi.nlm.nih.gov/pubmed/18509530
http://dx.doi.org/10.1371/journal.pone.0002275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386548/
https://www.ncbi.nlm.nih.gov/pubmed/18509530
http://dx.doi.org/10.1371/journal.pone.0002275

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