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Trypanosomiasis-Induced B Cell Apoptosis Results in Loss of Protective Anti-Parasite Antibody Responses and Abolishment of Vaccine-Induced Memory Responses

African trypanosomes of the Trypanosoma brucei species are extra-cellular parasites that cause human African trypanosomiasis (HAT) as well as infections in game animals and livestock. Trypanosomes are known to evade the immune response of their mammalian host by continuous antigenic variation of the...

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Detalles Bibliográficos
Autores principales: Radwanska, Magdalena, Guirnalda, Patrick, De Trez, Carl, Ryffel, Bernard, Black, Samuel, Magez, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386555/
https://www.ncbi.nlm.nih.gov/pubmed/18516300
http://dx.doi.org/10.1371/journal.ppat.1000078

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