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Mutation detection using ENDO1: Application to disease diagnostics in humans and TILLING and Eco-TILLING in plants
BACKGROUND: Most enzymatic mutation detection methods are based on the cleavage of heteroduplex DNA by a mismatch-specific endonuclease at mismatch sites and the analysis of the digestion product on a DNA sequencer. Important limitations of these methods are the availability of a mismatch-specific e...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386800/ https://www.ncbi.nlm.nih.gov/pubmed/18433472 http://dx.doi.org/10.1186/1471-2199-9-42 |