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Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect

BACKGROUND: Hydroxycamptothecin (HCPT) has been shown to have activity against a broad spectrum of cancers. In order to enhance its tissue-specific delivery and anticancer activity, we prepared HCPT-loaded nanoparticles made from poly(ethylene glycol)-poly(γ-benzyl-L-glutamate) (PEG-PBLG), and then...

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Detalles Bibliográficos
Autores principales: Wang, Anxun, Li, Su
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386803/
https://www.ncbi.nlm.nih.gov/pubmed/18454874
http://dx.doi.org/10.1186/1472-6750-8-46