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Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

Hedgehog (HH) signaling is one of the key pathways with major significance for embryogenesis, tumorigenesis, and stem cell maintenance. Glioma-associated oncogene 1 (GLI1) is a transcription factor that acts as the terminal signaling effector but also represents a pathway target gene. Here we report...

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Detalles Bibliográficos
Autores principales:	Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386930/ https://www.ncbi.nlm.nih.gov/pubmed/18378682 http://dx.doi.org/10.1074/jbc.M800299200

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