Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells

BACKGROUND: Hypoxia inducible factor-1 (HIF-1) is a transcription factor that functions to maintain cellular homeostasis in response to hypoxia. There is evidence that HIF-1 can also trigger apoptosis, possibly when cellular responses are inadequate to meet energy demands under hypoxic conditions. M...

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Detalles Bibliográficos
Autores principales: Malhotra, Ricky, Tyson, David W, Rosevear, Henry M, Brosius, Frank C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387135/
https://www.ncbi.nlm.nih.gov/pubmed/18447926
http://dx.doi.org/10.1186/1471-2261-8-9

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