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Mycolic Acid Modification by the mmaA4 Gene of M. tuberculosis Modulates IL-12 Production

Mycobacterium tuberculosis has evolved many strategies to evade elimination by the host immune system, including the selective repression of macrophage IL-12p40 production. To identify the M. tuberculosis genes responsible for this aspect of immune evasion, we used a macrophage cell line expressing...

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Detalles Bibliográficos
Autores principales:	Dao, Dee N., Sweeney, Kari, Hsu, Tsungda, Gurcha, Sudagar S., Nascimento, Ivan P., Roshevsky, Dan, Besra, Gurdyal S., Chan, John, Porcelli, Steven A., Jacobs, William R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390761/ https://www.ncbi.nlm.nih.gov/pubmed/18535659 http://dx.doi.org/10.1371/journal.ppat.1000081

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