Cargando…
The protective role of transferrin in Müller glial cells after iron-induced toxicity
PURPOSE: Transferrin (Tf) expression is enhanced by aging and inflammation in humans. We investigated the role of transferrin in glial protection. METHODS: We generated transgenic mice (Tg) carrying the complete human transferrin gene on a C57Bl/6J genetic background. We studied human (hTf) and mous...
Autores principales: | Picard, Emilie, Fontaine, Isabelle, Jonet, Laurent, Guillou, Florian, Behar-Cohen, Francine, Courtois, Yves, Jeanny, Jean-Claude |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391081/ https://www.ncbi.nlm.nih.gov/pubmed/18509548 |
Ejemplares similares
-
Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice
por: Picard, Emilie, et al.
Publicado: (2010) -
Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection
por: Daruich, Alejandra, et al.
Publicado: (2019) -
From Rust to Quantum Biology: The Role of Iron in Retina Physiopathology
por: Picard, Emilie, et al.
Publicado: (2020) -
Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration
por: Bigot, Karine, et al.
Publicado: (2020) -
PKCζ Mediates Breakdown of Outer Blood-Retinal Barriers in Diabetic Retinopathy
por: Omri, Samy, et al.
Publicado: (2013)