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Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias
Mounting evidence indicates that alterations of AKT signalling play important roles in cancer development. An earlier study discovered an oncogenic AKT1 gene mutation (AKT1 E17K) in breast, colorectal and ovarian cancers. The aim of this study was to see whether the AKT1 E17K mutation is common in b...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391109/ https://www.ncbi.nlm.nih.gov/pubmed/18392055 http://dx.doi.org/10.1038/sj.bjc.6604212 |