Quantitative techniques in (18)FDG PET scanning in oncology

The clinical applications of (18)F-fluoro-2-deoxyglucose ((18)FDG) positron emission tomography (PET) in oncology are becoming established. While simple static scanning techniques are used for the majority of routine clinical examinations, increasing use of PET in clinical trials to monitor treatmen...

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Detalles Bibliográficos
Autores principales: Castell, F, Cook, G J R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391128/
https://www.ncbi.nlm.nih.gov/pubmed/18475291
http://dx.doi.org/10.1038/sj.bjc.6604330
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author Castell, F
Cook, G J R
author_facet Castell, F
Cook, G J R
author_sort Castell, F
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description The clinical applications of (18)F-fluoro-2-deoxyglucose ((18)FDG) positron emission tomography (PET) in oncology are becoming established. While simple static scanning techniques are used for the majority of routine clinical examinations, increasing use of PET in clinical trials to monitor treatment response with (18)FDG and novel tracers reflecting different pharmacodynamic end points, often necessitates a more complex and quantitative analysis of radiopharmaceutical kinetics. A wide range of PET analysis techniques exist, ranging from simple visual analysis and semiquantitative methods to full dynamic studies with kinetic analysis. These methods are discussed, focusing particularly on the available methodologies that can be utilised in clinical trials.
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spelling pubmed-23911282009-09-10 Quantitative techniques in (18)FDG PET scanning in oncology Castell, F Cook, G J R Br J Cancer Minireview The clinical applications of (18)F-fluoro-2-deoxyglucose ((18)FDG) positron emission tomography (PET) in oncology are becoming established. While simple static scanning techniques are used for the majority of routine clinical examinations, increasing use of PET in clinical trials to monitor treatment response with (18)FDG and novel tracers reflecting different pharmacodynamic end points, often necessitates a more complex and quantitative analysis of radiopharmaceutical kinetics. A wide range of PET analysis techniques exist, ranging from simple visual analysis and semiquantitative methods to full dynamic studies with kinetic analysis. These methods are discussed, focusing particularly on the available methodologies that can be utilised in clinical trials. Nature Publishing Group 2008-05-20 2008-05-13 /pmc/articles/PMC2391128/ /pubmed/18475291 http://dx.doi.org/10.1038/sj.bjc.6604330 Text en Copyright © 2008 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Castell, F
Cook, G J R
Quantitative techniques in (18)FDG PET scanning in oncology
title Quantitative techniques in (18)FDG PET scanning in oncology
title_full Quantitative techniques in (18)FDG PET scanning in oncology
title_fullStr Quantitative techniques in (18)FDG PET scanning in oncology
title_full_unstemmed Quantitative techniques in (18)FDG PET scanning in oncology
title_short Quantitative techniques in (18)FDG PET scanning in oncology
title_sort quantitative techniques in (18)fdg pet scanning in oncology
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391128/
https://www.ncbi.nlm.nih.gov/pubmed/18475291
http://dx.doi.org/10.1038/sj.bjc.6604330
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