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Selective killing of HIV-1-positive macrophages and T cells by the Rev-dependent lentivirus carrying anthrolysin O from Bacillus anthracis

BACKGROUND: The ability of Human Immunodeficiency Virus (HIV) to persist in the body has proven to be a long-standing challenge to virus eradication. Current antiretroviral therapy cannot selectively destroy infected cells; it only halts active viral replication. With therapeutic cessation or interr...

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Detalles Bibliográficos
Autores principales: Young, Jessica, Tang, Zhongwei, Yu, Quan, Yu, Dongyang, Wu, Yuntao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391154/
https://www.ncbi.nlm.nih.gov/pubmed/18439272
http://dx.doi.org/10.1186/1742-4690-5-36