Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma

A 66-year old female with HIV-negative classic Kaposi's sarcoma responded to mTOR targeting by rapamycin. The response was well documented by PET-CT. This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in...

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Detalles Bibliográficos
Autores principales: Merimsky, Ofer, Jiveliouk, Irina, Sagi-Eisenberg, Ronit
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391286/
https://www.ncbi.nlm.nih.gov/pubmed/18509482
http://dx.doi.org/10.1155/2008/825093
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author Merimsky, Ofer
Jiveliouk, Irina
Sagi-Eisenberg, Ronit
author_facet Merimsky, Ofer
Jiveliouk, Irina
Sagi-Eisenberg, Ronit
author_sort Merimsky, Ofer
collection PubMed
description A 66-year old female with HIV-negative classic Kaposi's sarcoma responded to mTOR targeting by rapamycin. The response was well documented by PET-CT. This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in this disease.
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spelling pubmed-23912862008-05-28 Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma Merimsky, Ofer Jiveliouk, Irina Sagi-Eisenberg, Ronit Sarcoma Case Report A 66-year old female with HIV-negative classic Kaposi's sarcoma responded to mTOR targeting by rapamycin. The response was well documented by PET-CT. This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in this disease. Hindawi Publishing Corporation 2008 2008-05-15 /pmc/articles/PMC2391286/ /pubmed/18509482 http://dx.doi.org/10.1155/2008/825093 Text en Copyright © 2008 Ofer Merimsky et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Merimsky, Ofer
Jiveliouk, Irina
Sagi-Eisenberg, Ronit
Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title_full Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title_fullStr Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title_full_unstemmed Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title_short Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
title_sort targeting mtor in hiv-negative classic kaposi's sarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391286/
https://www.ncbi.nlm.nih.gov/pubmed/18509482
http://dx.doi.org/10.1155/2008/825093
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AT jivelioukirina targetingmtorinhivnegativeclassickaposissarcoma
AT sagieisenbergronit targetingmtorinhivnegativeclassickaposissarcoma

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