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No major tumorigenic role for β-catenin in serrated as opposed to conventional colorectal adenomas
Intracellular redistribution of β-catenin through mutation of the adenomatous polyposis coli (APC) gene has been proposed as an early tumorigenic event in most colorectal tumours. In serrated adenoma (SA), a newly recognised subtype of colorectal adenoma, APC mutations are uncommon, and the contribu...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394200/ https://www.ncbi.nlm.nih.gov/pubmed/12838317 http://dx.doi.org/10.1038/sj.bjc.6601070 |