The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro

Raman spectroscopy is an optical technique, which provides a measure of the molecular composition of tissue. Raman spectra were recorded in vitro from both benign and malignant prostate biopsies, and used to construct a diagnostic algorithm. The algorithm was able to correctly identify each patholog...

Descripción completa

Detalles Bibliográficos
Autores principales: Crow, P, Stone, N, Kendall, C A, Uff, J S, Farmer, J A M, Barr, H, Wright, M P J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394218/
https://www.ncbi.nlm.nih.gov/pubmed/12838309
http://dx.doi.org/10.1038/sj.bjc.6601059
_version_ 1782155366442729472
author Crow, P
Stone, N
Kendall, C A
Uff, J S
Farmer, J A M
Barr, H
Wright, M P J
author_facet Crow, P
Stone, N
Kendall, C A
Uff, J S
Farmer, J A M
Barr, H
Wright, M P J
author_sort Crow, P
collection PubMed
description Raman spectroscopy is an optical technique, which provides a measure of the molecular composition of tissue. Raman spectra were recorded in vitro from both benign and malignant prostate biopsies, and used to construct a diagnostic algorithm. The algorithm was able to correctly identify each pathological group studied with an overall accuracy of 89%. The technique shows promise as a method for objectively grading prostate cancer.
format Text
id pubmed-2394218
institution National Center for Biotechnology Information
language English
publishDate 2003
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-23942182009-09-10 The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro Crow, P Stone, N Kendall, C A Uff, J S Farmer, J A M Barr, H Wright, M P J Br J Cancer Molecular and Cellular Pathology Raman spectroscopy is an optical technique, which provides a measure of the molecular composition of tissue. Raman spectra were recorded in vitro from both benign and malignant prostate biopsies, and used to construct a diagnostic algorithm. The algorithm was able to correctly identify each pathological group studied with an overall accuracy of 89%. The technique shows promise as a method for objectively grading prostate cancer. Nature Publishing Group 2003-07-07 2003-07-01 /pmc/articles/PMC2394218/ /pubmed/12838309 http://dx.doi.org/10.1038/sj.bjc.6601059 Text en Copyright © 2003 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Molecular and Cellular Pathology
Crow, P
Stone, N
Kendall, C A
Uff, J S
Farmer, J A M
Barr, H
Wright, M P J
The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title_full The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title_fullStr The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title_full_unstemmed The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title_short The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
title_sort use of raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
topic Molecular and Cellular Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394218/
https://www.ncbi.nlm.nih.gov/pubmed/12838309
http://dx.doi.org/10.1038/sj.bjc.6601059
work_keys_str_mv AT crowp theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT stonen theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT kendallca theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT uffjs theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT farmerjam theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT barrh theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT wrightmpj theuseoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT crowp useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT stonen useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT kendallca useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT uffjs useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT farmerjam useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT barrh useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro
AT wrightmpj useoframanspectroscopytoidentifyandgradeprostaticadenocarcinomainvitro

Ejemplares similares