Progressive resistance of BTK-143 osteosarcoma cells to Apo2L/TRAIL-induced apoptosis is mediated by acquisition of DcR2/TRAIL-R4 expression: resensitisation with chemotherapy

Apo2 ligand (Apo2L, also known as TRAIL) is a member of the tumour necrosis factor (TNF) family of cytokines that selectively induces the death of cancer cells, but not of normal cells. We observed that recombinant Apo2L/TRAIL was proapoptotic in early-passage BTK-143 osteogenic sarcoma cells, induc...

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Detalles Bibliográficos
Autores principales: Bouralexis, S, Findlay, D M, Atkins, G J, Labrinidis, A, Hay, S, Evdokiou, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394221/
https://www.ncbi.nlm.nih.gov/pubmed/12838325
http://dx.doi.org/10.1038/sj.bjc.6601021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394221/
https://www.ncbi.nlm.nih.gov/pubmed/12838325
http://dx.doi.org/10.1038/sj.bjc.6601021

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