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New molecular pathways in angiogenesis
Angiogenesis has developed into a major area of cancer research. Recently, several newly identified signalling pathways have been shown to play a role in both normal and pathological (including tumour) angiogenesis. Several of the molecules involved in these pathways have potential as novel anti-can...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394258/ https://www.ncbi.nlm.nih.gov/pubmed/12865906 http://dx.doi.org/10.1038/sj.bjc.6601107 |
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author | Sullivan, D C Bicknell, R |
author_facet | Sullivan, D C Bicknell, R |
author_sort | Sullivan, D C |
collection | PubMed |
description | Angiogenesis has developed into a major area of cancer research. Recently, several newly identified signalling pathways have been shown to play a role in both normal and pathological (including tumour) angiogenesis. Several of the molecules involved in these pathways have potential as novel anti-cancer therapeutic targets including members of the ephrin/Eph receptor, Notch/delta, sprouty, hedgehog and roundabout/slit families. These developments are reviewed. |
format | Text |
id | pubmed-2394258 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-23942582009-09-10 New molecular pathways in angiogenesis Sullivan, D C Bicknell, R Br J Cancer Review Angiogenesis has developed into a major area of cancer research. Recently, several newly identified signalling pathways have been shown to play a role in both normal and pathological (including tumour) angiogenesis. Several of the molecules involved in these pathways have potential as novel anti-cancer therapeutic targets including members of the ephrin/Eph receptor, Notch/delta, sprouty, hedgehog and roundabout/slit families. These developments are reviewed. Nature Publishing Group 2003-07-21 2003-07-15 /pmc/articles/PMC2394258/ /pubmed/12865906 http://dx.doi.org/10.1038/sj.bjc.6601107 Text en Copyright © 2003 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Review Sullivan, D C Bicknell, R New molecular pathways in angiogenesis |
title | New molecular pathways in angiogenesis |
title_full | New molecular pathways in angiogenesis |
title_fullStr | New molecular pathways in angiogenesis |
title_full_unstemmed | New molecular pathways in angiogenesis |
title_short | New molecular pathways in angiogenesis |
title_sort | new molecular pathways in angiogenesis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394258/ https://www.ncbi.nlm.nih.gov/pubmed/12865906 http://dx.doi.org/10.1038/sj.bjc.6601107 |
work_keys_str_mv | AT sullivandc newmolecularpathwaysinangiogenesis AT bicknellr newmolecularpathwaysinangiogenesis |