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Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-β expression

Many cancers express Fas ligand (FasL/CD95L) in vivo, and can kill lymphoid cells by Fas-mediated apoptosis in vitro. However, overexpression of recombinant FasL in murine tumour allografts revealed a potential antitumour effect of FasL, via recruitment of neutrophils. Transforming growth factor-β1...

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Detalles Bibliográficos
Autores principales:	Houston, A, Bennett, M W, O'Sullivan, G C, Shanahan, F, O'Connell, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394303/ https://www.ncbi.nlm.nih.gov/pubmed/14520470 http://dx.doi.org/10.1038/sj.bjc.6601240

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