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Detection of p53 mutations in precancerous gastric tissue

Intestinal-type gastric cancer is preceded by gastritis and intestinal metaplasia. There is uncertainty regarding the stage at which genetic alterations in the p53 gene occur. Reactive oxygen species (ROS) may participate in the production of mutations and the inactivation of p53 is due to infection...

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Detalles Bibliográficos
Autores principales:	Morgan, C, Jenkins, G J S, Ashton, T, Griffiths, A P, Baxter, J N, Parry, E M, Parry, J M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394306/ https://www.ncbi.nlm.nih.gov/pubmed/14520466 http://dx.doi.org/10.1038/sj.bjc.6601302

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