Prospective study of high-dose chemotherapy and autologous peripheral stem cell transplantation in adult patients with advanced desmoplastic small round-cell tumour

A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WT1 fusion transcript detection was positive in the peripheral blood during follow-up in all p...

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Detalles Bibliográficos
Autores principales: Bertuzzi, A, Castagna, L, Quagliuolo, V, Ginanni, V, Compasso, S, Magagnoli, M, Balzarotti, M, Nozza, A, Siracusano, L, Timofeeva, I, Sarina, B, Parra, H Soto, Santoro, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394317/
https://www.ncbi.nlm.nih.gov/pubmed/14520438
http://dx.doi.org/10.1038/sj.bjc.6601304
Descripción
Sumario:A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WT1 fusion transcript detection was positive in the peripheral blood during follow-up in all patients. High-dose chemotherapy did not seem to change the results in desmoplastic small round-cell tumour.

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