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Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy

The role of Bax in the release of cytochrome c from mitochondria and the induction of apoptosis has been demonstrated in many systems. Using immunocytochemical staining, we observed that photodynamic therapy (PDT) with the photosensitiser Pc 4 induced Bax translocation from the cytosol to mitochondr...

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Detalles Bibliográficos
Autores principales: Chiu, S-M, Xue, L-Y, Usuda, J, Azizuddin, K, Oleinick, N L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394333/
https://www.ncbi.nlm.nih.gov/pubmed/14562036
http://dx.doi.org/10.1038/sj.bjc.6601298