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Non-invasive (19)F MR spectroscopy of 5-fluorocytosine to 5-fluorouracil conversion by recombinant Salmonella in tumours

The aim of this study was to evaluate the applicability of fluorine-19 magnetic resonance spectroscopy ((19)F MRS) for monitoring in vivo the conversion of 5-fluorocytosine (5-FC) to 5-fluorouracil (5-FU) after using an attenuated Salmonella Typhimurium strain recombinant to provide cytosine deamina...

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Detalles Bibliográficos
Autores principales:	Dresselaers, T, Theys, J, Nuyts, S, Wouters, B, de Bruijn, E, Anné, J, Lambin, P, Van Hecke, P, Landuyt, W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394413/ https://www.ncbi.nlm.nih.gov/pubmed/14583786 http://dx.doi.org/10.1038/sj.bjc.6601345

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