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Potentiation of ionising radiation by targeting tumour necrosis factor alpha using a bispecific antibody in human pancreatic cancer

The aim of this study was to treat carcinoembryonic antigen (CEA)-expressing pancreatic carcinoma cells with tumour necrosis factor alpha (TNFα) and simultaneous radiation therapy (RT), using a bispecific antibody (BAb) anti-TNFα/anti-CEA. TNFα used alone produced a dose-dependent inhibition of the...

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Detalles Bibliográficos
Autores principales:	Azria, D, Larbouret, C, Garambois, V, Kramar, A, Martineau, P, Robert, B, Aillères, N, Ychou, M, Dubois, J B, Pèlegrin, A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394444/ https://www.ncbi.nlm.nih.gov/pubmed/14612914 http://dx.doi.org/10.1038/sj.bjc.6601362

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