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Arginine deiminase: a potential inhibitor of angiogenesis and tumour growth

Hydrolysis of plasma arginine to citrulline by arginine deiminase (ADI) was recently shown to suppress lipopolysaccharide-induced nitric oxide (NO) synthesis. Since arginine is the precursor of NO, and the latter modulates angiogenesis, we explored whether ADI treatment significantly affected tube-l...

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Detalles Bibliográficos
Autores principales:	Park, I-S, Kang, S-W, Shin, Y-J, Chae, K-Y, Park, M-O, Kim, M-Y, Wheatley, D N, Min, B-H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394481/ https://www.ncbi.nlm.nih.gov/pubmed/12942125 http://dx.doi.org/10.1038/sj.bjc.6601181

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