Cargando…

Improved radiotracing of oxytocin receptor-expressing tumours using the new [(111)In]-DOTA-Lys(8)-deamino-vasotocin analogue

Oxytocin receptors (OTR) have been described in a number of tumours of different origin, and represent a new target for specific radiolabelled oxytocin (OT) analogues in cancer diagnosis and therapy. By linking the DOTA chelating agent to position 8 of the deamino derivative of Lys(8)-vasotocin (dLV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chini, B, Chinol, M, Cassoni, P, Papi, S, Reversi, A, Areces, L, Marrocco, T, Paganelli, G, Manning, M, Bussolati, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394487/ https://www.ncbi.nlm.nih.gov/pubmed/12942128 http://dx.doi.org/10.1038/sj.bjc.6601189

Ejemplares similares

Universal nomenclature for oxytocin–vasotocin ligand and receptor families
por: Theofanopoulou, Constantina, et al.
Publicado: (2021)

Oxytocin and vasotocin receptor variation and the evolution of human prosociality
por: Theofanopoulou, Constantina, et al.
Publicado: (2022)

[(111)In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study
por: Tatsi, Aikaterini, et al.
Publicado: (2012)

Effect of Deamino-8-D-Arginine Desmopressin in Uremic Bleeding
por: Hong, Sae-Yong, et al.
Publicado: (1996)

Arginine Vasotocin, the Social Neuropeptide of Amphibians and Reptiles
por: Wilczynski, Walter, et al.
Publicado: (2017)

Pre-clinical quantitative imaging and mouse-specific dosimetry for (111)In-labelled radiotracers
por: Denis-Bacelar, Ana M., et al.
Publicado: (2016)

The Evolution of Oxytocin and Vasotocin Receptor Genes in Jawed Vertebrates: A Clear Case for Gene Duplications Through Ancestral Whole-Genome Duplications
por: Ocampo Daza, Daniel, et al.
Publicado: (2022)

Oxytocin-Gly-Lys-Arg: A Novel Cardiomyogenic Peptide
por: Danalache, Bogdan A., et al.
Publicado: (2010)

A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers
por: Osborn, Megan, et al.
Publicado: (2019)

Constitutive and ligand-induced nuclear localization of oxytocin receptor
por: Kinsey, Conan G, et al.
Publicado: (2007)

Characterization of (111)In-labeled Glucose-Dependent Insulinotropic Polypeptide as a Radiotracer for Neuroendocrine Tumors
por: Willekens, Stefanie M. A., et al.
Publicado: (2018)

Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with (111)In in HEPES and MES buffer
por: Brom, Maarten, et al.
Publicado: (2012)

Imaging inflammation in atherosclerotic plaques, targeting SST(2) with [(111)In]In-DOTA-JR11
por: Meester, Eric J., et al.
Publicado: (2020)

Neuroanatomical Evidence That Kisspeptin Directly Regulates Isotocin and Vasotocin Neurons
por: Kanda, Shinji, et al.
Publicado: (2013)

Neuropeptides isotocin and arginine vasotocin in urophysis of three fish species
por: Gozdowska, Magdalena, et al.
Publicado: (2012)

Behavioral relevance of species-specific vasotocin anatomy in gregarious finches
por: Kelly, Aubrey M., et al.
Publicado: (2013)

Arginine Vasotocin Preprohormone Is Expressed in Surprising Regions of the Teleost Forebrain
por: Rodriguez-Santiago, Mariana, et al.
Publicado: (2017)

Development of a Potential Gallium-68-Labelled Radiotracer Based on DOTA-Curcumin for Colon-Rectal Carcinoma: From Synthesis to In Vivo Studies
por: Orteca, Giulia, et al.
Publicado: (2019)

The Role of [(68)Ga]Ga-DOTA-SSTR PET Radiotracers in Brain Tumors: A Systematic Review of the Literature and Ongoing Clinical Trials
por: Palmisciano, Paolo, et al.
Publicado: (2022)

(177)Lu-DOTA-HYNIC-Lys(Nal)-Urea-Glu: Biokinetics, Dosimetry, and Evaluation in Patients with Advanced Prostate Cancer
por: Santos-Cuevas, Clara, et al.
Publicado: (2018)

Arginine Vasotocin Regulation of Interspecific Cooperative Behaviour in a Cleaner Fish
por: Soares, Marta C., et al.
Publicado: (2012)

Commentary: Arginine Vasotocin Preprohormone Is Expressed in Surprising Regions of the Teleost Forebrain
por: Loveland, Jasmine L., et al.
Publicado: (2018)

Sensitive Periods, Vasotocin-Family Peptides, and the Evolution and Development of Social Behavior
por: Baran, Nicole M.
Publicado: (2017)

Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA(5m) chelators
por: Moon, Euy Sung, et al.
Publicado: (2020)

Development of Novel (111)-In-Labelled DOTA Urotensin II Analogues for Targeting the UT Receptor Overexpressed in Solid Tumours
por: Poret, Benjamin, et al.
Publicado: (2020)

Evaluation of a (68)Ga-Labeled DOTA-Tetrazine as a PET Alternative to (111)In-SPECT Pretargeted Imaging
por: Edem, Patricia E., et al.
Publicado: (2020)

Vasotocin Actions on Electric Behavior: Interspecific, Seasonal, and Social Context-Dependent Differences
por: Perrone, Rossana, et al.
Publicado: (2010)

Corrigendum: Commentary: Arginine Vasotocin Preprohormone Is Expressed in Surprising Regions of the Teleost Forebrain
por: Loveland, Jasmine L., et al.
Publicado: (2018)

Knock-out of vasotocin reduces reproductive success in female zebrafish, Danio rerio
por: Ramachandran, Divya, et al.
Publicado: (2023)

The combined activation of K(Ca)3.1 and inhibition of K(v)11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells
por: Pillozzi, Serena, et al.
Publicado: (2018)

Protocol for a placebo-controlled, within-participants crossover trial evaluating the efficacy of intranasal oxytocin to improve pain and function among women with chronic pelvic musculoskeletal pain
por: Rash, Joshua A, et al.
Publicado: (2017)

Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics
por: Manning, M, et al.
Publicado: (2012)

Status-Dependent Vasotocin Modulation of Dominance and Subordination in the Weakly Electric Fish Gymnotus omarorum
por: Perrone, Rossana, et al.
Publicado: (2018)

Vasotocin receptor gene genotypes moderate the relationship between cortical thickness and sensory processing
por: Lee, Seonkyoung, et al.
Publicado: (2023)

Comparing Gly(11)/dAla(11)-Replacement vs. the in-Situ Neprilysin-Inhibition Approach on the Tumor-targeting Efficacy of the (111)In-SB3/(111)In-SB4 Radiotracer Pair
por: Lymperis, Emmanouil, et al.
Publicado: (2019)

Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [(111)In-DOTA]MG11—first estimates for clinical translation
por: Kaloudi, Aikaterini, et al.
Publicado: (2016)

Human Absorbed Dose Estimation of (111)In-DOTA-PR81 as a Novel High Potential Agent for Breast Cancer Imaging
por: Yousefnia, Hassan, et al.
Publicado: (2022)

Reduction of the Renal Radioactivity of (111)In-DOTA-Labeled Antibody Fragments with a Linkage Cleaved by the Renal Brush Border Membrane Enzymes
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

Neonatal oxytocin gives the tempo of social and feeding behaviors
por: Muscatelli, Françoise, et al.
Publicado: (2022)

Basic physics of radiotracers
por: Barnes, W Earl
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_35i3i1nshimjm4nr4tmbfv1rvk