The Retinoic Acid Receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production

BACKGROUND: We have recently demonstrated that all-trans-retinoic acid (ATRA) and 9-cis-retinoic acid (9-cis RA) promote IL-4, IL-5 and IL-13 synthesis, while decreasing IFN-γ and TNF-α expression by activated human T cells and reduces the synthesis of IL-12p70 from accessory cells. Here, we have de...

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Detalles Bibliográficos
Autores principales: Dawson, Harry D, Collins, Gary, Pyle, Robert, Key, Michael, Taub, Dennis D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394516/
https://www.ncbi.nlm.nih.gov/pubmed/18416830
http://dx.doi.org/10.1186/1471-2172-9-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394516/
https://www.ncbi.nlm.nih.gov/pubmed/18416830
http://dx.doi.org/10.1186/1471-2172-9-16

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