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LongSAGE profiling of nine human embryonic stem cell lines

To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel...

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Autores principales: Hirst, Martin, Delaney, Allen, Rogers, Sean A, Schnerch, Angelique, Persaud, Deryck R, O'Connor, Michael D, Zeng, Thomas, Moksa, Michelle, Fichter, Keith, Mah, Diana, Go, Anne, Morin, Ryan D, Baross, Agnes, Zhao, Yongjun, Khattra, Jaswinder, Prabhu, Anna-Liisa, Pandoh, Pawan, McDonald, Helen, Asano, Jennifer, Dhalla, Noreen, Ma, Kevin, Lee, Stephanie, Ally, Adrian, Chahal, Neil, Menzies, Stephanie, Siddiqui, Asim, Holt, Robert, Jones, Steven, Gerhard, Daniela S, Thomson, James A, Eaves, Connie J, Marra, Marco A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394759/
https://www.ncbi.nlm.nih.gov/pubmed/17570852
http://dx.doi.org/10.1186/gb-2007-8-6-r113
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author Hirst, Martin
Delaney, Allen
Rogers, Sean A
Schnerch, Angelique
Persaud, Deryck R
O'Connor, Michael D
Zeng, Thomas
Moksa, Michelle
Fichter, Keith
Mah, Diana
Go, Anne
Morin, Ryan D
Baross, Agnes
Zhao, Yongjun
Khattra, Jaswinder
Prabhu, Anna-Liisa
Pandoh, Pawan
McDonald, Helen
Asano, Jennifer
Dhalla, Noreen
Ma, Kevin
Lee, Stephanie
Ally, Adrian
Chahal, Neil
Menzies, Stephanie
Siddiqui, Asim
Holt, Robert
Jones, Steven
Gerhard, Daniela S
Thomson, James A
Eaves, Connie J
Marra, Marco A
author_facet Hirst, Martin
Delaney, Allen
Rogers, Sean A
Schnerch, Angelique
Persaud, Deryck R
O'Connor, Michael D
Zeng, Thomas
Moksa, Michelle
Fichter, Keith
Mah, Diana
Go, Anne
Morin, Ryan D
Baross, Agnes
Zhao, Yongjun
Khattra, Jaswinder
Prabhu, Anna-Liisa
Pandoh, Pawan
McDonald, Helen
Asano, Jennifer
Dhalla, Noreen
Ma, Kevin
Lee, Stephanie
Ally, Adrian
Chahal, Neil
Menzies, Stephanie
Siddiqui, Asim
Holt, Robert
Jones, Steven
Gerhard, Daniela S
Thomson, James A
Eaves, Connie J
Marra, Marco A
author_sort Hirst, Martin
collection PubMed
description To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state.
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spelling pubmed-23947592008-05-24 LongSAGE profiling of nine human embryonic stem cell lines Hirst, Martin Delaney, Allen Rogers, Sean A Schnerch, Angelique Persaud, Deryck R O'Connor, Michael D Zeng, Thomas Moksa, Michelle Fichter, Keith Mah, Diana Go, Anne Morin, Ryan D Baross, Agnes Zhao, Yongjun Khattra, Jaswinder Prabhu, Anna-Liisa Pandoh, Pawan McDonald, Helen Asano, Jennifer Dhalla, Noreen Ma, Kevin Lee, Stephanie Ally, Adrian Chahal, Neil Menzies, Stephanie Siddiqui, Asim Holt, Robert Jones, Steven Gerhard, Daniela S Thomson, James A Eaves, Connie J Marra, Marco A Genome Biol Method To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state. BioMed Central 2007 2007-06-14 /pmc/articles/PMC2394759/ /pubmed/17570852 http://dx.doi.org/10.1186/gb-2007-8-6-r113 Text en Copyright © 2007 Hirst et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Method
Hirst, Martin
Delaney, Allen
Rogers, Sean A
Schnerch, Angelique
Persaud, Deryck R
O'Connor, Michael D
Zeng, Thomas
Moksa, Michelle
Fichter, Keith
Mah, Diana
Go, Anne
Morin, Ryan D
Baross, Agnes
Zhao, Yongjun
Khattra, Jaswinder
Prabhu, Anna-Liisa
Pandoh, Pawan
McDonald, Helen
Asano, Jennifer
Dhalla, Noreen
Ma, Kevin
Lee, Stephanie
Ally, Adrian
Chahal, Neil
Menzies, Stephanie
Siddiqui, Asim
Holt, Robert
Jones, Steven
Gerhard, Daniela S
Thomson, James A
Eaves, Connie J
Marra, Marco A
LongSAGE profiling of nine human embryonic stem cell lines
title LongSAGE profiling of nine human embryonic stem cell lines
title_full LongSAGE profiling of nine human embryonic stem cell lines
title_fullStr LongSAGE profiling of nine human embryonic stem cell lines
title_full_unstemmed LongSAGE profiling of nine human embryonic stem cell lines
title_short LongSAGE profiling of nine human embryonic stem cell lines
title_sort longsage profiling of nine human embryonic stem cell lines
topic Method
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394759/
https://www.ncbi.nlm.nih.gov/pubmed/17570852
http://dx.doi.org/10.1186/gb-2007-8-6-r113
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