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LongSAGE profiling of nine human embryonic stem cell lines
To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394759/ https://www.ncbi.nlm.nih.gov/pubmed/17570852 http://dx.doi.org/10.1186/gb-2007-8-6-r113 |
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author | Hirst, Martin Delaney, Allen Rogers, Sean A Schnerch, Angelique Persaud, Deryck R O'Connor, Michael D Zeng, Thomas Moksa, Michelle Fichter, Keith Mah, Diana Go, Anne Morin, Ryan D Baross, Agnes Zhao, Yongjun Khattra, Jaswinder Prabhu, Anna-Liisa Pandoh, Pawan McDonald, Helen Asano, Jennifer Dhalla, Noreen Ma, Kevin Lee, Stephanie Ally, Adrian Chahal, Neil Menzies, Stephanie Siddiqui, Asim Holt, Robert Jones, Steven Gerhard, Daniela S Thomson, James A Eaves, Connie J Marra, Marco A |
author_facet | Hirst, Martin Delaney, Allen Rogers, Sean A Schnerch, Angelique Persaud, Deryck R O'Connor, Michael D Zeng, Thomas Moksa, Michelle Fichter, Keith Mah, Diana Go, Anne Morin, Ryan D Baross, Agnes Zhao, Yongjun Khattra, Jaswinder Prabhu, Anna-Liisa Pandoh, Pawan McDonald, Helen Asano, Jennifer Dhalla, Noreen Ma, Kevin Lee, Stephanie Ally, Adrian Chahal, Neil Menzies, Stephanie Siddiqui, Asim Holt, Robert Jones, Steven Gerhard, Daniela S Thomson, James A Eaves, Connie J Marra, Marco A |
author_sort | Hirst, Martin |
collection | PubMed |
description | To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state. |
format | Text |
id | pubmed-2394759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-23947592008-05-24 LongSAGE profiling of nine human embryonic stem cell lines Hirst, Martin Delaney, Allen Rogers, Sean A Schnerch, Angelique Persaud, Deryck R O'Connor, Michael D Zeng, Thomas Moksa, Michelle Fichter, Keith Mah, Diana Go, Anne Morin, Ryan D Baross, Agnes Zhao, Yongjun Khattra, Jaswinder Prabhu, Anna-Liisa Pandoh, Pawan McDonald, Helen Asano, Jennifer Dhalla, Noreen Ma, Kevin Lee, Stephanie Ally, Adrian Chahal, Neil Menzies, Stephanie Siddiqui, Asim Holt, Robert Jones, Steven Gerhard, Daniela S Thomson, James A Eaves, Connie J Marra, Marco A Genome Biol Method To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state. BioMed Central 2007 2007-06-14 /pmc/articles/PMC2394759/ /pubmed/17570852 http://dx.doi.org/10.1186/gb-2007-8-6-r113 Text en Copyright © 2007 Hirst et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Method Hirst, Martin Delaney, Allen Rogers, Sean A Schnerch, Angelique Persaud, Deryck R O'Connor, Michael D Zeng, Thomas Moksa, Michelle Fichter, Keith Mah, Diana Go, Anne Morin, Ryan D Baross, Agnes Zhao, Yongjun Khattra, Jaswinder Prabhu, Anna-Liisa Pandoh, Pawan McDonald, Helen Asano, Jennifer Dhalla, Noreen Ma, Kevin Lee, Stephanie Ally, Adrian Chahal, Neil Menzies, Stephanie Siddiqui, Asim Holt, Robert Jones, Steven Gerhard, Daniela S Thomson, James A Eaves, Connie J Marra, Marco A LongSAGE profiling of nine human embryonic stem cell lines |
title | LongSAGE profiling of nine human embryonic stem cell lines |
title_full | LongSAGE profiling of nine human embryonic stem cell lines |
title_fullStr | LongSAGE profiling of nine human embryonic stem cell lines |
title_full_unstemmed | LongSAGE profiling of nine human embryonic stem cell lines |
title_short | LongSAGE profiling of nine human embryonic stem cell lines |
title_sort | longsage profiling of nine human embryonic stem cell lines |
topic | Method |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394759/ https://www.ncbi.nlm.nih.gov/pubmed/17570852 http://dx.doi.org/10.1186/gb-2007-8-6-r113 |
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